Newer Drugs in the Treatment of Hypertension
نویسنده
چکیده
IN A PREVIOUS study it was demonstrated that hexamethonium, although a potent anticholihergic compound capable of lowering blood pressure for short periods, is not satisfactory as a single drug for the longterm treatment of severe hypertension.' While this study w-as in progress, preliminary clinical iinvestigationi of hydralazine (Apresoline) demonstrated this compound to be partially effective in the treatment of hypertension.2-5 Hydralazine possesses complex actions which include the neutralization of pressor substances,6-9 central vasodepression,"0 "1 weak
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